0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 0000002 - Document - Audit Information link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 9952156 - Disclosure - Organization and Nature of Operations link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Inventory link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Property, Equipment and Software link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Revenue link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Stock-based Compensation link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - TeSera Transaction link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Employee Benefit Plan link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Segment Reporting link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Inventory, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Property, Equipment and Software (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Stock-based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - 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Disclosure - Summary of Significant Accounting Policies - Schedule of Antidilutive Securities Excluded from the Calculation of Diluted Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Marketable Securities - Available-For-Sale Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Inventory, Net - Schedule of Inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Inventory, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Property, Equipment and Software (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Stockholders' Equity (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Revenue - Incyte Corporation (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Revenue - Gilead Sciences Inc (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Revenue - Zai Lab (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Revenue - Provention (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Revenue - Manufacturing Service Agreements (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Revenue - NIAID Contract (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Revenue - Product Sales (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Stock-based Compensation - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Stock-based Compensation - Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Stock-based Compensation - Option Pricing Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Stock-based Compensation - Stock Option and Restricted Stock Unit Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - TeSera Transaction (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Income Taxes - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Income Taxes - Components of the Company's Deferred Tax Assets (Liabilities) (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Income Taxes - Valuation Allowance Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Income Taxes - Reconciliation of Reported Estimated Income Tax Benefit (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Income Taxes - Reconciliation of the Beginning and Ending Amount of Gross Unrecognized Tax Benefits (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Income Taxes - Income Tax Paid Table (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Employee Benefit Plan (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Segment Reporting (Details) link:presentationLink link:calculationLink link:definitionLink