0001125345 2026-09-03 2026-09-03 0001125345 1 2026-09-03 2026-09-03 shares iso4217:USD pure 0001125345 EX-FILING FEES N/A S-8 S-8 MACROGENICS, INC. Equity false Common Stock, $0.01 par value per share true 1250000 4.03 5037500 0.0001381 695.68 5037500 695.68 0 695.68 Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement shall also cover any additional shares of the Registrant’s Common Stock (“Common Stock”) that become issuable under the MacroGenics, Inc. 2023 Equity Incentive Plan (the “2023 EIP”) by reason of any stock dividend, stock split, recapitalization or other similar transaction.Represents shares of common stock that were added to the shares reserved for future issuance under the 2023 EIP upon approval of an amendment to the 2023 EIP at the Registrant’s 2026 Annual Meeting of Stockholders. Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act. The price per share and aggregate offering price are calculated on the basis of $4.03, the average of the high and low price of the Registrant’s Common Stock as reported on the Nasdaq Global Select Market on August 31, 2026.