0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 9952156 - Disclosure - Nature of Operations link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Fair Value of Financial Instruments link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Inventory, Net link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Royalty Monetization Arrangement link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Revenue link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - In-Licensing Arrangement link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Net Income (Loss) Per Share link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Segment Reporting link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Subsequent Event link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Fair Value of Financial Instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Royalty Monetization Arrangement (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Net Income (Loss) Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Segment Reporting (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Nature of Operations - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Fair Value of Financial Instruments (Details) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Inventory, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Royalty Monetization Arrangement - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Royalty Monetization Arrangement - Rollforward (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Stockholders' Equity (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Revenue- Incyte Corporation (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Revenue- Incyte Corporation (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Revenue- Gilead Science Inc (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Revenue - Provention (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Revenue - Sanofi S.A. (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Stock-Based Compensation - Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Stock-Based Compensation - Option Pricing Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Stock-Based Compensation - Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Stock-based Compensation - Restricted Stock Unit Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - In-Licensing Arrangement (Detail) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Net Income (Loss) Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Segment Reporting (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Subsequent Event (Details) link:presentationLink link:calculationLink link:definitionLink