0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 0000002 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 0000003 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 0000004 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:presentationLink link:calculationLink link:definitionLink 0000005 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 0000006 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 0000007 - Disclosure - Nature of Operations link:presentationLink link:calculationLink link:definitionLink 0000008 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 0000009 - Disclosure - Fair Value of Financial Instruments link:presentationLink link:calculationLink link:definitionLink 0000010 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 0000011 - Disclosure - Inventory, Net link:presentationLink link:calculationLink link:definitionLink 0000012 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 0000013 - Disclosure - Revenue link:presentationLink link:calculationLink link:definitionLink 0000014 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 0000015 - Disclosure - In-Licensing Arrangement link:presentationLink link:calculationLink link:definitionLink 9954471 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9954472 - Disclosure - Fair Value of Financial Instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 9954473 - Disclosure - Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9954474 - Disclosure - Inventory, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 9954475 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9954476 - Disclosure - Fair Value of Financial Instruments (Details) link:presentationLink link:calculationLink link:definitionLink 9954477 - Disclosure - Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9954478 - Disclosure - Inventory, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9954479 - Disclosure - Stockholders' Equity (Details) link:presentationLink link:calculationLink link:definitionLink 9954480 - Disclosure - Revenue- Incyte Corporation (Details) link:presentationLink link:calculationLink link:definitionLink 9954480 - Disclosure - Revenue- Incyte Corporation (Details) link:presentationLink link:calculationLink link:definitionLink 9954481 - Disclosure - Revenue- Gilead Science Inc (Details) link:presentationLink link:calculationLink link:definitionLink 9954482 - Disclosure - Revenue - Provention (Details) link:presentationLink link:calculationLink link:definitionLink 9954483 - Disclosure - Revenue - NIAID Contract (Details) link:presentationLink link:calculationLink link:definitionLink 9954484 - Disclosure - Stock-Based Compensation - Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9954485 - Disclosure - Stock-Based Compensation - Option Pricing Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 9954486 - Disclosure - Stock-Based Compensation - Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9954487 - Disclosure - Stock-based Compensation - Restricted Stock Unit Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9954488 - Disclosure - In-Licensing Arrangement (Detail) link:presentationLink link:calculationLink link:definitionLink