Committee Composition Independent Director Audit Committee Nominating and Governance Committee Human Capital Management Committee Science and Technology Committee Karen Ferrante, M.D. Independent Director Nominating and Governance Committee Science and Technology Committee William Heiden Independent Director Audit Committee Human Capital Management Committee Edward Hurwitz Independent Director Nominating and Governance Committee Science and Technology Committee Scott Jackson Independent Director Audit Committee Meenu Chhabra Karson Independent Director Audit Committee Human Capital Management Committee Scott Koenig, M.D., Ph.D. Margaret A. Liu, M.D. Independent Director Nominating and Governance Committee Science and Technology Committee Federica “Freddi” O’Brien Independent Director Audit Committee Human Capital Management Committee Jay Siegel M.D. Independent Director Human Capital Management Committee Science and Technology Committee David Stump, M.D. Independent Director Nominating and Governance Committee Science and Technology Committee = Independent Director = Chairperson = Member = Chairman of the Board