Ownership Profile

SHAREHOLDER BREAKDOWN

Shareholder Holders Value ($MM) % O/S Shares
Institution 179 272.29 93.22 45,802,140
Mutual Fund 258 134.94 41.15 20,199,141
Insider 10 10.62 3.39 1,666,600

INSTITUTIONAL SHAREHOLDER ROTATION

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 79 22.49 7.74 3,802,678
Sellers 112 -35.78 10.72 -5,268,639
Net -13.29 2.98 -1,465,961

INSTITUTIONAL SHAREHOLDER CONCENTRATION

Value ($MM) % O/S Shares
Total Inst. 307.37 100.55 49,395,632
Top 10 Inst. 182.18 59.10 29,029,702
Top 20 Inst. 238.08 77.32 37,983,537
Top 50 Inst. 284.74 93.42 45,891,493

INSTITUTIONAL SHAREHOLDER STYLE

Holders Value ($MM) % Inst Shares Shares
Growth 41 71.13 24.86 12,216,881
Aggressive Growth 3 1.75 0.61 300,042
Core Growth 30 30.63 10.70 5,256,897
Growth 8 38.76 13.55 6,659,942
Income 5 1.43 0.49 242,345
Income Value 1 0.71 0.25 122,003
Yield 4 0.72 0.25 120,342
Index 23 70.32 24.32 11,949,942
Other 58 115.98 39.00 19,161,696
Broker Dealer 12 2.60 0.91 447,212
GARP 23 72.34 23.89 11,740,727
Hedge Fund 22 34.78 12.01 5,899,441
Specialty -- --
VC Private Equity 1 6.25 2.19 1,074,316
Value 27 11.07 3.81 1,870,230
Core Value 21 8.97 3.07 1,510,343
Deep Value 6 2.10 0.73 359,887

TOP HOLDERS: INSTITUTIONAL INVESTOR

Holder Shares Held % O/S Share Change Filing Date
Bellevue Asset Management AG 6,119,150 12.45 245,794 3/31/20
Invesco Advisers, Inc. 4,452,073 9.06 -30,463 3/31/20
BlackRock Institutional Trust Company, N.A. 3,799,841 7.73 7,116 3/31/20
The Vanguard Group, Inc. 3,249,328 6.61 39,798 3/31/20
Wasatch Global Investors Inc 2,613,035 5.32 415,334 3/31/20
Johnson & Johnson 1,923,077 3.93 -- 12/31/18
State Street Global Advisors (US) 1,915,848 3.90 -14,762 3/31/20
Columbia Wanger Asset Management, LLC 1,839,789 3.74 488,259 3/31/20
Millennium Management LLC 1,629,019 3.32 -685,812 3/31/20
Hood River Capital Management LLC 1,488,542 3.03 -16,810 3/31/20
Dimensional Fund Advisors, L.P. 1,358,595 2.76 53,858 3/31/20
Koenig (Scott) 1,164,150 2.37 79,895 3/20/20
InterWest Partners 1,074,316 2.19 -- 3/31/20
Rhenman & Partners Asset Management AB 1,000,000 2.04 -60,000 3/31/20
Nuveen LLC 891,555 1.81 184,660 3/31/20
Pinnacle Associates Ltd. 762,370 1.55 -96,575 3/31/20
Candriam Belgium S.A. 747,763 1.52 -7,225 12/31/19
Geode Capital Management, L.L.C. 743,518 1.51 52,516 3/31/20
UBS Asset Management (Switzerland) 629,525 1.28 -81,503 3/31/20
Fidelity Management & Research Company 582,043 1.18 -248,400 3/31/20
Northern Trust Investments, Inc. 555,546 1.13 -4,342 3/31/20
Renaissance Technologies LLC 468,123 0.95 16,000 3/31/20
BlackRock Advisors (UK) Limited 462,534 0.94 103,792 4/30/20
Opaleye Management Inc. 422,300 0.86 221,800 3/31/20
D. E. Shaw & Co., L.P. 410,352 0.84 -198,800 3/31/20
BlackRock Asset Management Ireland Limited 370,788 0.75 21,899 3/31/20
Ikarian Capital LLC 360,030 0.73 350,000 3/31/20
Citadel Advisors LLC 311,395 0.63 61,864 3/31/20
Victory Capital Management Inc. 307,935 0.63 -15,723 3/31/20
Charles Schwab Investment Management, Inc. 305,584 0.62 5,920 3/31/20
Two Sigma Investments, LP 291,139 0.59 -36,069 3/31/20
BlackRock Financial Management, Inc. 276,424 0.56 14,625 3/31/20
Macquarie Investment Management 275,000 0.56 -- 3/31/20
Jacobs Levy Equity Management, Inc. 258,396 0.53 258,396 3/31/20
Rock Springs Capital Management LP 230,000 0.47 -- 3/31/20
Granahan Investment Management, Inc. 224,638 0.46 -1,313 3/31/20
Principal Global Investors (Equity) 220,094 0.45 -49,832 3/31/20
Wellington Management Company, LLP 208,040 0.42 -5,460 3/31/20
BofA Global Research (US) 195,803 0.40 161,497 3/31/20
Numeric Investors LLC 190,762 0.39 37,444 3/31/20
BlackRock Investment Management, LLC 189,661 0.39 8,469 3/31/20
Point72 Asset Management, L.P. 177,063 0.36 177,063 3/31/20
AXA Rosenberg Investment Management LLC 176,000 0.36 -- 3/31/20
Acadian Asset Management LLC 160,265 0.33 133,855 3/31/20
Bonvini Ezio 154,208 0.31 -- 3/20/20
MFS Investment Management 153,996 0.31 24,375 3/31/20
Karrels (James) 152,460 0.31 4,473 3/20/20
Dafna Capital Management, LLC 150,000 0.31 -- 3/31/20
Bogle Investment Management, L.P. 127,100 0.26 -22,439 3/31/20
Goldman Sachs & Company, Inc. 122,320 0.25 7,410 3/31/20

* Insider values reflect direct beneficial ownership.

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