Ownership Profile

SHAREHOLDER BREAKDOWN

Shareholder Holders Value ($MM) % O/S Shares
Institution 209 1,043.99 98.47 41,556,414
Mutual Fund 245 383.39 39.15 16,521,645
Insider 8 9.94 1.05 441,877

INSTITUTIONAL SHAREHOLDER ROTATION

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 107 145.82 13.81 5,826,743
Sellers 78 -65.37 6.86 -2,893,790
Net -- 80.45 6.95 2,932,953

INSTITUTIONAL SHAREHOLDER CONCENTRATION

Value ($MM) % O/S Shares
Total Inst. 1,043.99 98.47 41,556,414
Top 10 Inst. 592.92 55.84 23,566,143
Top 20 Inst. 803.52 75.68 31,936,572
Top 50 Inst. 966.10 90.99 38,398,074

INSTITUTIONAL SHAREHOLDER STYLE

Holders Value ($MM) % Inst Shares Shares
Growth 47 166.31 15.72 6,632,920
Aggressive Growth 2 0.06 0.01 2,828
Core Growth 36 77.88 7.38 3,113,406
Growth 9 88.37 8.33 3,516,686
Income 6 14.68 1.38 584,284
Income Value 4 14.54 1.37 578,081
Yield 2 0.14 0.01 6,203
Index 21 162.10 15.27 6,445,799
Other 73 501.90 47.32 19,969,995
Broker Dealer 15 10.13 0.95 402,592
GARP 24 289.55 27.29 11,515,775
Hedge Fund 32 175.07 16.52 6,972,994
Specialty 1 0.11 0.01 4,318
VC/Private Equi 1 27.03 2.55 1,074,316
Value 22 21.61 2.04 861,386
Core Value 17 18.06 1.71 720,780
Deep Value 5 3.55 0.33 140,606

TOP HOLDERS: INSTITUTIONAL INVESTOR

Holder Shares Held % O/S Share Change Filing Date
OppenheimerFunds, Inc. 3,949,370 9.36 15,464 3/31/18
Fidelity Management & Research Company 3,411,035 8.08 -228,502 3/31/18
Bellevue Asset Management AG 3,163,563 7.50 -1,250 3/31/18
BlackRock Institutional Trust Company, N.A. 2,435,861 5.77 -38,109 3/31/18
T. Rowe Price Associates, Inc. 2,258,991 5.35 2,250,691 3/31/18
Boxer Capital, L.L.C. 2,200,000 5.21 -- 3/31/18
Johnson & Johnson 1,923,077 4.56 -- 3/23/18
The Vanguard Group, Inc. 1,689,223 4.00 124,567 3/31/18
EcoR1 Capital, LLC 1,450,606 3.44 309,812 3/31/18
Point72 Asset Management, L.P. 1,084,417 2.57 -- 3/31/18
InterWest Partners 1,074,316 2.55 -- 3/31/18
State Street Global Advisors (US) 1,040,602 2.47 -5,334 3/31/18
Wasatch Advisors, Inc. 1,015,036 2.41 -13,407 3/31/18
Koenig (Scott) 1,004,358 2.38 79,898 3/23/18
Aviva Holdings Ltd. 977,426 2.32 190,166 3/31/18
Millennium Management LLC 897,982 2.13 415,681 3/31/18
Pinnacle Associates Ltd. 790,100 1.87 -26,875 3/31/18
Hood River Capital Management LLC 646,109 1.53 13,588 3/31/18
Franklin Advisers, Inc. 479,500 1.14 -- 3/31/18
Prosight Capital 445,000 1.05 -162,696 3/31/18
Renaissance Technologies LLC 399,323 0.95 98,800 3/31/18
Northern Trust Investments, Inc. 389,505 0.92 1,150 3/31/18
Baker Bros. Advisors LP 363,676 0.86 -- 3/31/18
Voya Investment Management LLC 363,433 0.86 -213,748 3/31/18
UBS Asset Management (Switzerland) 344,742 0.82 -19,959 3/31/18
Columbia Wanger Asset Management, LLC 336,728 0.80 -73,274 3/31/18
Geode Capital Management, L.L.C. 313,860 0.74 15,701 3/31/18
Rhenman & Partners Asset Management AB 300,000 0.71 -8,604 3/31/18
Dimensional Fund Advisors, L.P. 289,484 0.69 -- 3/31/18
Rock Springs Capital Management LP 275,000 0.65 50,000 3/31/18
683 Capital Management LLC 250,000 0.59 250,000 3/31/18
Spark Investment Management LLC 226,000 0.54 71,400 3/31/18
Granahan Investment Management, Inc. 219,264 0.52 43,866 3/31/18
Monashee Investment Management, LLC 197,500 0.47 197,500 3/31/18
Victory Capital Management Inc. 176,600 0.42 176,600 3/31/18
Charles Schwab Investment Management, Inc. 174,463 0.41 -643 3/31/18
Morgan Stanley & Co. LLC 165,802 0.39 97,947 3/31/18
Bonvini Ezio 154,208 0.37 -- 3/23/18
Alyeska Investment Group, L.P. 150,000 0.36 150,000 3/31/18
Deutsche Asset Management Americas 148,502 0.35 -32,667 3/31/18
Eventide Asset Management, LLC 147,000 0.35 -- 3/31/18
Nuveen LLC 143,023 0.34 2,054 3/31/18
Jacobs Levy Equity Management, Inc. 137,497 0.33 -15,539 3/31/18
Sphera Funds Management Ltd. 135,000 0.32 -3,700 3/31/18
OxFORD Asset Management 129,715 0.31 129,715 3/31/18
BlackRock Investment Management, LLC 119,315 0.28 -11,293 3/31/18
Karrels (James) 114,847 0.27 6,516 3/23/18
Columbia Threadneedle Investments (US) 100,380 0.24 15,486 3/31/18
Citadel LLC 99,130 0.23 43,101 3/31/18
CVI Holdings LLC 97,505 0.23 97,505 3/31/18

* Insider values reflect direct beneficial ownership.

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