Ownership Profile

SHAREHOLDER BREAKDOWN

Shareholder Holders Value ($MM) % O/S Shares
Institution 205 531.07 84.79 41,361,343
Mutual Fund 283 322.51 45.99 22,435,009
Insider 8 8.58 1.12 545,069

INSTITUTIONAL SHAREHOLDER ROTATION

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 102 70.34 11.28 5,503,276
Sellers 83 -105.98 14.62 -7,129,953
Net -- -35.64 3.34 -1,626,677

INSTITUTIONAL SHAREHOLDER CONCENTRATION

Value ($MM) % O/S Shares
Total Inst. 531.07 84.79 41,361,343
Top 10 Inst. 305.14 49.43 24,109,802
Top 20 Inst. 390.92 63.36 30,904,800
Top 50 Inst. 481.31 77.38 37,748,185

INSTITUTIONAL SHAREHOLDER STYLE

Holders Value ($MM) % Inst Shares Shares
Growth 50 109.37 17.43 8,499,994
Aggressive Growth 3 2.32 0.38 182,996
Core Growth 36 44.01 7.10 3,462,655
Growth 11 63.04 9.95 4,854,343
Income 7 8.51 1.37 666,122
Income Value 4 7.13 1.15 561,764
Yield 3 1.37 0.21 104,358
Index 21 107.61 17.35 8,462,453
Other 66 230.78 37.30 18,194,394
Broker Dealer 12 2.99 0.48 235,377
GARP 20 149.92 24.28 11,846,143
Hedge Fund 29 44.74 7.22 3,522,680
Specialty 1 0.64 0.07 32,078
VC/Private Equi 4 32.49 5.24 2,558,116
Value 25 17.01 2.74 1,337,351
Core Value 20 14.03 2.26 1,102,833
Deep Value 5 2.98 0.48 234,518

TOP HOLDERS: INSTITUTIONAL INVESTOR

Holder Shares Held % O/S Share Change Filing Date
OppenheimerFunds, Inc. 4,446,841 9.12 359,061 12/31/18
Bellevue Asset Management AG 4,350,265 8.92 635,551 12/31/18
BlackRock Institutional Trust Company, N.A. 3,011,373 6.17 38,350 12/31/18
The Vanguard Group, Inc. 2,551,127 5.23 280,586 12/31/18
T. Rowe Price Associates, Inc. 2,250,287 4.61 -32,859 12/31/18
Fidelity Management & Research Company 2,062,631 4.23 -557,580 12/31/18
Johnson & Johnson 1,923,077 3.94 -- 12/31/18
State Street Global Advisors (US) 1,345,529 2.76 106,414 12/31/18
Cohen Private Ventures, LLC 1,084,417 2.22 1,084,417 12/31/18
Koenig (Scott) 1,084,255 2.22 39,897 1/3/19
InterWest Partners 1,074,316 2.20 -- 12/31/18
Wasatch Advisors, Inc. 1,044,977 2.14 -1,420 12/31/18
Dimensional Fund Advisors, L.P. 808,201 1.66 225,690 12/31/18
Hood River Capital Management LLC 678,550 1.39 9,910 12/31/18
Candriam Luxembourg S.A. 542,987 1.11 186,387 12/31/18
Rhenman & Partners Asset Management AB 542,186 1.11 200,600 12/31/18
Candriam Belgium S.A. 539,100 1.11 -- 1/31/19
Pinnacle Associates Ltd. 538,228 1.10 -56,068 12/31/18
UBS Asset Management (Switzerland) 520,069 1.07 41,530 12/31/18
Columbia Wanger Asset Management, LLC 506,384 1.04 61,141 12/31/18
Point72 Asset Management, L.P. 487,240 1.00 -647,177 12/31/18
Northern Trust Investments, Inc. 474,290 0.97 -1,379 12/31/18
Franklin Advisers, Inc. 459,335 0.94 -- 12/31/18
Geode Capital Management, L.L.C. 455,874 0.93 39,246 12/31/18
683 Capital Management LLC 384,970 0.79 49,336 12/31/18
Sofinnova Ventures, Inc. 332,921 0.68 332,921 12/31/18
Spark Investment Management LLC 304,500 0.62 15,800 12/31/18
Millennium Management LLC 257,680 0.53 30,622 12/31/18
Charles Schwab Investment Management, Inc. 244,672 0.50 -2,213 12/31/18
Nuveen LLC 242,245 0.50 -1,578 12/31/18
Granahan Investment Management, Inc. 240,488 0.49 -6,428 12/31/18
Renaissance Technologies LLC 196,100 0.40 37,077 12/31/18
Prosight Capital 194,129 0.40 -263,346 12/31/18
Arctic Fund Management AS 193,517 0.40 -85,890 9/30/18
Numeric Investors LLC 189,586 0.39 129,679 12/31/18
Voya Investment Management LLC 184,693 0.38 -728,285 12/31/18
BlackRock Financial Management, Inc. 180,788 0.37 96,659 12/31/18
OxFORD Asset Management 161,486 0.33 71,906 12/31/18
Principal Global Investors (Equity) 158,661 0.33 456 12/31/18
361 Capital LLC 154,717 0.32 154,717 12/31/18
Bonvini Ezio 154,208 0.32 53,264 3/23/18
Opaleye Management Inc. 150,000 0.31 150,000 12/31/18
Jacobs Levy Equity Management, Inc. 142,866 0.29 5,000 12/31/18
Goldman Sachs Asset Management (US) 142,679 0.29 35,837 12/31/18
Arrowstreet Capital, Limited Partnership 138,690 0.28 115,027 12/31/18
BlackRock Investment Management, LLC 135,680 0.28 4,197 12/31/18
Karrels (James) 135,487 0.28 12,640 1/24/19
Squarepoint Capital LLP 120,131 0.25 76,247 12/31/18
Columbia Threadneedle Investments (US) 117,213 0.24 11,307 12/31/18
Vident Investment Advisory, LLC 108,539 0.22 4,053 12/31/18

* Insider values reflect direct beneficial ownership.

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