Ownership Profile

SHAREHOLDER BREAKDOWN

Shareholder	Holders	Value ($MM)	% O/S	Shares
Institution	204	622.80	100.56	62,913,341
Mutual Fund	208	261.26	38.96	24,168,630
Insider	9	24.65	2.64	1,649,621

INSTITUTIONAL SHAREHOLDER ROTATION

Shareholder	Holders	Value Chg ($MM)	% O/S	Share Change
Buyers	101	65.77	10.18	6,371,782
Sellers	104	-69.92	13.07	-8,174,800
Net		-4.15	2.88	-1,803,018

INSTITUTIONAL SHAREHOLDER CONCENTRATION

	Value ($MM)	% O/S	Shares
Total Inst.	647.45	103.20	64,562,962
Top 10 Inst.	398.59	65.13	40,744,949
Top 20 Inst.	504.64	81.22	50,813,398
Top 50 Inst.	600.24	96.17	60,163,171

INSTITUTIONAL SHAREHOLDER STYLE

	Holders	Value ($MM)	% Inst Shares	Shares
Growth	42	140.01	22.50	14,076,556
Aggressive Growth	4	2.56	0.38	239,948
Core Growth	28	35.92	5.30	3,313,718
Growth	10	101.53	16.82	10,522,890
Income	6	2.82	0.36	222,245
Income Value	2	2.52	0.31	190,886
Yield	4	0.30	0.05	31,359
Index	30	144.02	23.77	14,871,762
Other	73	298.30	47.88	29,953,046
Broker Dealer	14	10.76	1.78	1,111,986
GARP	25	116.52	17.69	11,068,198
Hedge Fund	31	141.85	23.57	14,746,586
Specialty	1	0.19	0.02	12,640
VC Private Equity	2	28.99	4.82	3,013,636
Value	28	33.66	5.48	3,427,537
Core Value	20	8.12	1.33	833,206
Deep Value	8	25.55	4.15	2,594,331

TOP HOLDERS: INSTITUTIONAL INVESTOR

Holder	Shares Held	% O/S	Share Change	Filing Date
Bellevue Asset Management AG	9,953,313	15.91	--	12/31/23
T. Rowe Price Investment Management, Inc.	5,639,994	9.02	148,042	12/31/23
BlackRock Institutional Trust Company, N.A.	4,938,702	7.89	143,003	12/31/23
Armistice Capital LLC	4,572,000	7.31	-140,000	12/31/23
The Vanguard Group, Inc.	4,309,394	6.89	-105,530	12/31/23
RA Capital Management, LP	4,053,077	6.48	288,206	12/31/23
Frazier Healthcare Partners	2,401,704	3.84	598,500	12/31/23
State Street Global Advisors (US)	2,174,022	3.48	873,621	12/31/23
Geode Capital Management, L.L.C.	1,404,068	2.24	84,068	12/31/23
Koenig (Scott)	1,298,675	2.08	--	3/22/24
SilverArc Capital Management, LLC	1,258,641	2.01	-5,517	12/31/23
Dimensional Fund Advisors, L.P.	1,214,900	1.94	-6,345	12/31/23
Rock Springs Capital Management LP	1,178,796	1.88	--	12/31/23
Acadian Asset Management LLC	1,057,693	1.69	-313,703	12/31/23
JP Morgan Asset Management	1,015,080	1.62	46,567	12/31/23
Wasatch Global Investors Inc	989,579	1.58	-307,995	3/31/24
Millennium Management LLC	862,965	1.38	-1,175,923	12/31/23
BlackRock Financial Management, Inc.	844,412	1.35	-14,957	12/31/23
Charles Schwab Investment Management, Inc.	833,500	1.33	8,111	12/31/23
T. Rowe Price Associates, Inc.	812,883	1.30	750,706	3/31/24
Federated MDTA LLC	803,375	1.28	-126,701	12/31/23
Renaissance Technologies LLC	763,527	1.22	98,377	12/31/23
Pinnacle Associates Ltd.	647,235	1.03	-40,745	3/31/24
Perceptive Advisors LLC	611,932	0.98	611,932	12/31/23
Nuveen LLC	603,930	0.97	-330,468	12/31/23
Northern Trust Investments, Inc.	497,187	0.79	7,859	12/31/23
Goldman Sachs Asset Management, L.P.	492,229	0.79	98,414	12/31/23
Integral Health Asset Management, LLC	450,000	0.72	450,000	12/31/23
Macquarie Investment Management	420,000	0.67	--	12/31/23
PanAgora Asset Management Inc.	398,944	0.64	20,284	12/31/23
Northern Trust Global Investments	277,292	0.44	-3,550	12/31/23
Principal Global Investors (Equity)	267,876	0.43	-7,674	12/31/23
Morgan Stanley & Co. LLC	260,578	0.42	25,750	12/31/23
Connor, Clark & Lunn Investment Management Ltd.	244,196	0.39	104,945	12/31/23
Wellington Management Company, LLP	238,123	0.38	-10,397	12/31/23
ClariVest Asset Management LLC	186,847	0.30	89,247	12/31/23
Citadel Advisors LLC	182,484	0.29	71,902	12/31/23
BlackRock Investment Management, LLC	174,185	0.28	-7,446	12/31/23
Karrels (James)	171,452	0.27	-30,000	3/22/24
MFS Investment Management	165,107	0.26	-29,097	12/31/23
DWS Investment S.A.	161,900	0.26	161,900	12/31/23
Barclays Bank PLC	157,425	0.25	23,364	12/31/23
Arrowstreet Capital, Limited Partnership	156,493	0.25	156,493	12/31/23
BlackRock Advisors (UK) Limited	155,883	0.25	-132	3/31/24
Dafna Capital Management, LLC	152,250	0.24	-106,246	12/31/23
Susquehanna Portfolio Strategies, LLC	149,184	0.24	149,184	12/31/23
BlackRock Asset Management Ireland Limited	144,572	0.23	1,513	12/31/23
BofA Global Research (US)	142,418	0.23	-64,354	12/31/23
Atom Investors LP	139,090	0.22	109,441	12/31/23
BNY Mellon Asset Management	134,059	0.21	-25,808	3/31/24

* Insider values reflect direct beneficial ownership.