Ownership Profile

SHAREHOLDER BREAKDOWN

Shareholder	Holders	Value ($MM)	% O/S	Shares
Institution	205	882.78	97.04	41,008,097
Mutual Fund	266	443.01	50.46	21,322,103
Insider	6	6.93	0.70	294,728

INSTITUTIONAL SHAREHOLDER ROTATION

Shareholder	Holders	Value Chg ($MM)	% O/S	Share Change
Buyers	89	60.25	6.67	2,819,517
Sellers	104	-113.81	12.61	-5,330,581
Net	--	-53.56	5.94	-2,511,064

INSTITUTIONAL SHAREHOLDER CONCENTRATION

	Value ($MM)	% O/S	Shares
Total Inst.	882.78	97.04	41,008,097
Top 10 Inst.	515.86	56.15	23,727,110
Top 20 Inst.	672.53	73.99	31,269,599
Top 50 Inst.	820.07	90.16	38,100,684

INSTITUTIONAL SHAREHOLDER STYLE

	Holders	Value ($MM)	% Inst Shares	Shares
Growth	44	174.35	19.22	8,120,477
Aggressive Growth	1	0.03	--	1,488
Core Growth	33	84.22	9.30	3,929,203
Growth	10	90.10	9.91	4,189,786
Income	5	13.80	1.53	645,247
Income Value	2	12.10	1.34	564,535
Yield	3	1.70	0.19	80,712
Index	23	171.97	18.98	8,021,346
Other	66	393.41	43.44	18,358,132
Broker Dealer	14	6.05	0.67	282,098
GARP	22	249.55	27.54	11,639,582
Hedge Fund	28	114.69	12.68	5,357,077
Specialty	1	0.08	0.01	5,059
VC/Private Equi	1	23.03	2.54	1,074,316
Value	29	26.59	2.94	1,240,602
Core Value	23	21.60	2.38	1,007,605
Deep Value	6	4.99	0.55	232,997

TOP HOLDERS: INSTITUTIONAL INVESTOR

Holder	Shares Held	% O/S	Share Change	Filing Date
OppenheimerFunds, Inc.	4,087,780	9.67	-21,760	9/30/18
Bellevue Asset Management AG	3,714,714	8.79	457,389	9/30/18
BlackRock Institutional Trust Company, N.A.	2,973,023	7.04	100,224	9/30/18
Fidelity Management & Research Company	2,620,211	6.20	-420,983	9/30/18
T. Rowe Price Associates, Inc.	2,283,146	5.40	47,175	9/30/18
The Vanguard Group, Inc.	2,270,541	5.37	165,937	9/30/18
Johnson & Johnson	1,923,077	4.55	--	3/23/18
EcoR1 Capital, LLC	1,481,086	3.50	30,480	9/30/18
State Street Global Advisors (US)	1,239,115	2.93	-277,997	9/30/18
Point72 Asset Management, L.P.	1,134,417	2.68	50,000	9/30/18
InterWest Partners	1,074,316	2.54	--	9/30/18
Wasatch Advisors, Inc.	1,046,397	2.48	35,297	9/30/18
Koenig (Scott)	1,044,358	2.47	40,000	11/13/18
Voya Investment Management LLC	912,978	2.16	7,226	9/30/18
Hood River Capital Management LLC	668,640	1.58	-3,779	9/30/18
Aviva Holdings Ltd.	664,785	1.57	-312,641	9/30/18
Pinnacle Associates Ltd.	594,296	1.41	-87,644	9/30/18
Dimensional Fund Advisors, L.P.	582,511	1.38	293,527	9/30/18
UBS Asset Management (Switzerland)	478,539	1.13	-8,485	9/30/18
Northern Trust Investments, Inc.	475,669	1.13	9,262	9/30/18
Franklin Advisers, Inc.	459,335	1.09	-20,280	9/30/18
Prosight Capital	457,475	1.08	-161,040	9/30/18
Columbia Wanger Asset Management, LLC	445,243	1.05	-45,414	9/30/18
Geode Capital Management, L.L.C.	416,628	0.99	39,526	9/30/18
Candriam Belgium S.A.	356,600	0.84	265,000	9/30/18
Candriam Luxembourg S.A.	356,600	0.84	265,000	9/30/18
Rhenman & Partners Asset Management AB	341,586	0.81	16,586	9/30/18
683 Capital Management LLC	335,634	0.79	73,034	9/30/18
Spark Investment Management LLC	288,700	0.68	-90,300	9/30/18
Rock Springs Capital Management LP	275,000	0.65	--	9/30/18
Granahan Investment Management, Inc.	246,916	0.58	6,925	9/30/18
Charles Schwab Investment Management, Inc.	246,885	0.58	20,845	9/30/18
Nuveen LLC	243,823	0.58	4,022	9/30/18
Millennium Management LLC	227,058	0.54	-198,241	9/30/18
DekaBank Deutsche Girozentrale	193,600	0.46	175,500	9/30/18
Arctic Fund Management AS	193,517	0.46	-85,890	8/31/18
Renaissance Technologies LLC	159,023	0.38	-113,376	9/30/18
Principal Global Investors (Equity)	158,205	0.37	4,084	9/30/18
Bonvini Ezio	154,208	0.36	53,264	3/23/18
Eventide Asset Management, LLC	147,000	0.35	--	9/30/18
Jacobs Levy Equity Management, Inc.	137,866	0.33	-30,404	9/30/18
BlackRock Investment Management, LLC	131,483	0.31	-674	9/30/18
Karrels (James)	114,847	0.27	6,516	3/23/18
Goldman Sachs & Company, Inc.	111,138	0.26	63,056	9/30/18
Goldman Sachs Asset Management (US)	106,842	0.25	20,381	9/30/18
Columbia Threadneedle Investments (US)	105,906	0.25	-3,394	9/30/18
Victory Capital Management Inc.	105,770	0.25	-61,400	9/30/18
BNY Mellon Asset Management	105,200	0.25	713	9/30/18
Allianz Global Investors U.S. LLC	104,511	0.25	8,824	9/30/18
Vident Investment Advisory, LLC	104,486	0.25	-6,963	9/30/18

* Insider values reflect direct beneficial ownership.