Ownership Profile

SHAREHOLDER BREAKDOWN

Shareholder	Holders	Value ($MM)	% O/S	Shares
Institution	194	421.78	95.16	58,844,720
Mutual Fund	185	150.95	35.33	21,823,954
Insider	6	11.38	2.70	1,666,833

INSTITUTIONAL SHAREHOLDER ROTATION

Shareholder	Holders	Value Chg ($MM)	% O/S	Share Change
Buyers	88	45.94	10.37	6,415,213
Sellers	116	-48.15	11.09	-6,857,941
Net		-2.21	0.72	-442,728

INSTITUTIONAL SHAREHOLDER CONCENTRATION

	Value ($MM)	% O/S	Shares
Total Inst.	433.16	97.85	60,511,553
Top 10 Inst.	256.99	57.96	35,842,067
Top 20 Inst.	337.89	76.29	47,174,527
Top 50 Inst.	403.74	91.15	56,366,312

INSTITUTIONAL SHAREHOLDER STYLE

	Holders	Value ($MM)	% Inst Shares	Shares
Growth	42	97.64	22.07	13,645,345
Aggressive Growth	3	2.93	0.66	409,031
Core Growth	30	22.26	5.06	3,128,088
Growth	9	72.44	16.35	10,108,226
Income	6	1.31	0.30	182,858
Income Value	2	1.26	0.28	175,316
Yield	4	0.05	0.01	7,542
Index	24	106.46	24.02	14,851,093
Other	72	188.14	42.44	26,242,056
Broker Dealer	17	11.47	2.59	1,600,083
GARP	19	48.62	10.96	6,780,439
Hedge Fund	35	115.84	26.13	16,158,330
Specialty	--			--
VC Private Equity	1	12.21	2.75	1,703,204
Value	23	21.22	4.76	2,942,862
Core Value	16	2.65	0.57	350,952
Deep Value	7	18.58	4.19	2,591,910

TOP HOLDERS: INSTITUTIONAL INVESTOR

Holder	Shares Held	% O/S	Share Change	Filing Date
Bellevue Asset Management AG	9,609,913	15.54	29,950	3/31/23
Armistice Capital LLC	5,960,000	9.64	-132,000	3/31/23
BlackRock Institutional Trust Company, N.A.	4,723,720	7.64	-103,651	3/31/23
The Vanguard Group, Inc.	4,468,399	7.23	24,035	3/31/23
T. Rowe Price Investment Management, Inc.	2,913,405	4.71	36,677	3/31/23
Millennium Management LLC	1,954,350	3.16	-852,885	3/31/23
Frazier Healthcare Partners	1,703,204	2.75	1,703,204	3/31/23
Two Sigma Investments, LP	1,654,755	2.68	-184,788	3/31/23
Assenagon Asset Management S.A.	1,492,512	2.41	--	3/31/23
SilverArc Capital Management, LLC	1,361,809	2.20	749,334	3/31/23
Wasatch Global Investors Inc	1,321,220	2.14	-921,142	3/31/23
State Street Global Advisors (US)	1,303,266	2.11	11,853	3/31/23
Koenig (Scott)	1,270,683	2.05	53,268	4/3/23
Acadian Asset Management LLC	1,230,052	1.99	173,362	3/31/23
Geode Capital Management, L.L.C.	1,163,696	1.88	34,353	3/31/23
Rock Springs Capital Management LP	1,123,096	1.82	--	3/31/23
Dimensional Fund Advisors, L.P.	1,066,303	1.72	310,479	3/31/23
BlackRock Financial Management, Inc.	1,005,673	1.63	154,417	3/31/23
Federated Hermes MDTA LLC	955,892	1.55	-40,090	3/31/23
Baker Bros. Advisors LP	892,579	1.44	--	3/31/23
Nuveen LLC	683,617	1.11	166,058	3/31/23
Charles Schwab Investment Management, Inc.	621,543	1.01	212,180	3/31/23
EcoR1 Capital, LLC	619,192	1.00	-498,263	3/31/23
Renaissance Technologies LLC	574,823	0.93	91,700	3/31/23
Morgan Stanley & Co. LLC	521,692	0.84	-10,205	3/31/23
Northern Trust Investments, Inc.	457,803	0.74	-10,113	3/31/23
Macquarie Investment Management	420,000	0.68	--	3/31/23
PanAgora Asset Management Inc.	382,999	0.62	87,421	3/31/23
Pinnacle Associates Ltd.	373,473	0.60	6,863	3/31/23
Invesco Capital Management LLC	335,506	0.54	38,249	3/31/23
Susquehanna International Group, LLP	307,188	0.50	232,866	3/31/23
Jacobs Levy Equity Management, Inc.	304,122	0.49	248,386	3/31/23
Principal Global Investors (Equity)	273,260	0.44	5,480	3/31/23
Marshall Wace LLP	257,948	0.42	257,948	3/31/23
Ikarian Capital LLC	250,000	0.40	250,000	3/31/23
Citadel Advisors LLC	248,972	0.40	-208,072	3/31/23
Northern Trust Global Investments	247,015	0.40	-8,480	3/31/23
Sessa Capital	244,864	0.40	--	3/31/23
HRT Financial LP	231,927	0.38	92,914	3/31/23
Goldman Sachs Asset Management, L.P.	222,144	0.36	-32,464	3/31/23
Karrels (James)	191,776	0.31	--	4/3/23
BlackRock Investment Management, LLC	190,819	0.31	-1,472	3/31/23
BofA Global Research (US)	179,872	0.29	18,589	3/31/23
DWS Investment GmbH	161,900	0.26	161,900	3/31/23
Alpha DNA Investment Management LLC	156,937	0.25	156,937	3/31/23
D. E. Shaw & Co., L.P.	151,555	0.25	-342,372	3/31/23
MFS Investment Management	149,528	0.24	50,931	3/31/23
Cubist Systematic Strategies, LLC	146,232	0.24	-140,647	3/31/23
Trexquant Investment LP	143,062	0.23	119,342	3/31/23
BNY Mellon Asset Management	142,016	0.23	-6,982	3/31/23

* Insider values reflect direct beneficial ownership.