Ownership Profile

SHAREHOLDER BREAKDOWN

Shareholder	Holders	Value ($MM)	% O/S	Shares
Institution	215	695.35	99.11	62,075,589
Mutual Fund	211	250.75	36.20	22,493,119
Insider	9	24.65	2.63	1,649,621

INSTITUTIONAL SHAREHOLDER ROTATION

Shareholder	Holders	Value Chg ($MM)	% O/S	Share Change
Buyers	115	85.74	11.89	7,435,641
Sellers	87	-91.93	12.48	-7,804,684
Net		-6.20	0.59	-369,043

INSTITUTIONAL SHAREHOLDER CONCENTRATION

	Value ($MM)	% O/S	Shares
Total Inst.	720.01	101.74	63,725,210
Top 10 Inst.	434.13	63.79	39,955,131
Top 20 Inst.	546.84	78.71	49,298,496
Top 50 Inst.	662.72	94.03	58,891,889

INSTITUTIONAL SHAREHOLDER STYLE

	Holders	Value ($MM)	% Inst Shares	Shares
Growth	45	143.70	22.20	13,902,863
Aggressive Growth	4	2.56	0.38	239,948
Core Growth	32	39.75	5.05	3,162,402
Growth	9	101.38	16.77	10,500,513
Income	6	2.83	0.35	222,245
Income Value	2	2.52	0.30	190,886
Yield	4	0.31	0.05	31,359
Index	31	182.88	22.25	13,936,495
Other	77	318.97	48.92	30,637,072
Broker Dealer	15	22.36	2.92	1,827,838
GARP	28	127.40	17.94	11,233,517
Hedge Fund	32	163.14	27.06	16,951,145
Specialty	1	0.19	0.02	12,640
VC Private Equity	1	5.89	0.98	611,932
Value	29	39.21	4.49	2,812,877
Core Value	21	12.36	1.58	989,760
Deep Value	8	26.84	2.91	1,823,117

TOP HOLDERS: INSTITUTIONAL INVESTOR

Holder	Shares Held	% O/S	Share Change	Filing Date
Bellevue Asset Management AG	9,953,313	15.89	--	12/31/23
T. Rowe Price Investment Management, Inc.	5,639,994	9.00	148,042	12/31/23
BlackRock Institutional Trust Company, N.A.	4,790,878	7.65	-147,824	3/31/24
Armistice Capital LLC	4,572,000	7.30	-140,000	12/31/23
RA Capital Management, LP	4,053,077	6.47	288,206	12/31/23
The Vanguard Group, Inc.	3,667,400	5.86	-641,994	3/31/24
Frazier Life Sciences Management, L.P.	2,401,704	3.83	598,500	12/31/23
State Street Global Advisors (US)	2,174,022	3.47	873,621	12/31/23
Geode Capital Management, L.L.C.	1,404,068	2.24	84,068	12/31/23
Koenig (Scott)	1,298,675	2.07	--	3/22/24
SilverArc Capital Management, LLC	1,258,641	2.01	-5,517	12/31/23
Rock Springs Capital Management LP	1,178,796	1.88	--	12/31/23
Dimensional Fund Advisors, L.P.	1,051,259	1.68	-163,641	3/31/24
Wasatch Global Investors Inc	989,579	1.58	-307,995	3/31/24
JP Morgan Asset Management	944,616	1.51	-70,464	3/31/24
Millennium Management LLC	862,965	1.38	-1,175,923	12/31/23
T. Rowe Price Associates, Inc.	843,372	1.35	768,295	3/31/24
Federated MDTA LLC	803,375	1.28	-126,701	12/31/23
Renaissance Technologies LLC	763,527	1.22	98,377	12/31/23
Pinnacle Associates Ltd.	647,235	1.03	-40,745	3/31/24
Perceptive Advisors LLC	611,932	0.98	611,932	12/31/23
Nuveen LLC	603,930	0.96	-330,468	12/31/23
Susquehanna International Group, LLP	531,922	0.85	451,700	3/31/24
Charles Schwab Investment Management, Inc.	522,946	0.83	-310,554	3/31/24
BlackRock Financial Management, Inc.	508,648	0.81	-335,764	3/31/24
Northern Trust Investments, Inc.	497,187	0.79	7,859	12/31/23
Goldman Sachs Asset Management, L.P.	492,229	0.79	98,414	12/31/23
Acadian Asset Management LLC	473,413	0.76	-584,280	3/31/24
PanAgora Asset Management Inc.	463,430	0.74	64,486	3/31/24
Integral Health Asset Management, LLC	450,000	0.72	450,000	12/31/23
Macquarie Investment Management	420,000	0.67	--	12/31/23
Connor, Clark & Lunn Investment Management Ltd.	418,282	0.67	174,086	3/31/24
Principal Global Investors (Equity)	344,603	0.55	76,727	3/31/24
Citi Investment Research (US)	305,076	0.49	258,605	3/31/24
Northern Trust Global Investments	277,292	0.44	-3,550	12/31/23
Morgan Stanley & Co. LLC	260,578	0.42	25,750	12/31/23
Wellington Management Company, LLP	238,123	0.38	-10,397	12/31/23
TD Asset Management Inc.	213,448	0.34	138,400	3/31/24
Banque Pictet & Cie S.A.	208,698	0.33	208,698	3/31/24
Citadel Advisors LLC	182,484	0.29	71,902	12/31/23
Karrels (James)	171,452	0.27	-30,000	3/22/24
MFS Investment Management	165,107	0.26	-29,097	12/31/23
BlackRock Investment Management, LLC	163,785	0.26	-10,400	3/31/24
DWS Investment S.A.	161,900	0.26	161,900	12/31/23
Barclays Bank PLC	157,425	0.25	23,364	12/31/23
Arrowstreet Capital, Limited Partnership	156,493	0.25	156,493	12/31/23
Dafna Capital Management, LLC	152,250	0.24	-106,246	12/31/23
BlackRock Advisors (UK) Limited	151,867	0.24	-4,016	4/30/24
BlackRock Asset Management Ireland Limited	146,475	0.23	1,903	3/31/24
BofA Global Research (US)	142,418	0.23	-64,354	12/31/23

* Insider values reflect direct beneficial ownership.